I te 10 o Pēpuere, 2025, ka pānuitia e CARsgen Therapeutics kua tutuki i te tangata tuatahi i rongoatia ki te rongoā BCMA CAR-T allogeneic i whakawhanakehia i runga i te tūāpapa THANK-u Plus™ te urupare tino pakari (sCR) me te iti o te mate toenga (MRD) i te aromatawai o te Rā-28. I whakawhanakehia i roto i te whare, ko te tūāpapa THANK-u Plus™ he hangarau CAR-T allogeneic auaha i hangaia hei wikitoria i ngā wero urunga i roto i te rongoā CAR-T.
Ko te tūroro, i kitea he myeloma maha kua hoki mai/ātete, momo IgA-λ (R-ISS Stage II), kua toru ngā momo rongoā whakakotahi i mua, me te whakawhitinga pūtau take hematopoietic autologous. Whai muri i te whanaketanga o te mate i muri i te maimoatanga hou, i whakaurua te tūroro ki te whakamātautau haumanu. Whai muri i te werohanga o ngā pūtau CAR T i te taumata horopeta iti rawa e ai ki te kawa haumanu, i pāngia te tūroro e te mate tuku cytokine (CRS) Tau 1, i whakahaerea paitia me ngā rongoā antipyretic me te tocilizumab, ā, kāore te tūroro i whakaatu i te mate neurotoxicity e pā ana ki ngā pūtau ārai mate (ICANS) me ētahi atu pānga kino ārai mate e pā ana ki te CAR-T, e whakaatu ana i te āhua haumaru pai whānui.
Kua whakawhanakehia tēnei rongoā CAR-T hei rongoā i te myeloma maha kua hoki mai/ua koretake te mate (R/R MM) me te leukemia pūtau plasma kua hoki mai/ua koretake te mate (R/R PCL). E matapaetia ana ka puta he whakahōutanga raraunga anō i te haurua tuarua o tēnei tau.
I tēnei wā, he maha tonu ngā whakamātautau haumanu o ngā hangarau hou hei ārai i te matepukupuku i Haina e rapu ana i ngā tūroro. Mēnā kei te hiahia koe ki te kōrero mō ngā rongoā me ngā hangarau hou, ka taea e koe te whakapā atu ki te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing.
Tau Waea：4008803716
Email：myimmnet@163.com
Ngā Tohutoro
2.https://www.prnasia.com/
Wā tuku: 11-Pepuere-2025