Nō nā tata nei, i pānuitia e Bayer kua whakaaetia e te Whakahaere Hua Hauora ā-Motu o Haina (NMPA) te rongoā hou, arā, te sevabertinib, hei rongoā mō ngā tūroro pakeke e pangia ana e te mate pukupuku pūkahukahu kore-pūtau iti (NSCLC) kāore e taea te tango, e horapa ana rānei, ā, kei a rātou ngā whakarerekētanga ira HER2 (ERBB2) e whakahohe ana, ā, kua pāngia e te whanaketanga o te mate i muri i te iti rawa i te kotahi te rongoā pūnaha o mua.
Ko te tikanga o tēnei, ahakoa nō tēhea whenua koe, ka taea e koe te uru atu ki tēnei rongoā tika matatau o te ao mā te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing.
Sevabertinib: Te arotahi tika ki ngā whakarerekētanga HER2
He rongoā hou a Sevabertinib, he rongoā waha, he rongoā whakahurihuri mō te tyrosine kinase iti. He kaha tana aukati i te HER2 whakarerekētanga (tae atu ki ngā whakaurunga HER2 exon 20 me ngā whakarerekētanga pūwāhi) me te EGFR. Ki te whakatauritea ki ngā TKI kore e taea te huri, ka whakaratohia e te TKI whakahurihuri he aukati wā poto, tika hoki o te ūnga, ka taea ai te maimoatanga whakahaere ake, ā, ka taea hoki te whakaiti i ngā pānga taha mō te wā roa.
Te Whakatenatena i ngā Raraunga Hauora: Ngā Urupare Hira, Ngā Painga Pumau
Ko te whakaaetanga o te sevabertinib i ahu mai i ngā hua pai mai i te whakamātautau SOHO-01 Wāhanga I/II o te ao maha-pokapū:
- Mō ngā tūroro kāore anō kia whiwhi i te rongoā ADC e arohia ana ki te HER2 i mua
I eke te reiti urupare whāinga (ORR) ki te 64%, tae atu ki te 2.5% o ngā whakautu kua oti me te 62% o ngā whakautu hapa. Ko te roanga waenga o te urupare he 9.2 marama.
- Mō ngā tūroro i whiwhi i mua i te rongoā ADC e arohia ana e te HER2
I te 38% tonu te ORR, tae atu ki te 5.5% o ngā whakautu kua oti, me te 33% o ngā whakautu kāore i te tino tika. Ko te roanga o te whakautu toharite he 7 marama.
He ngāwari te whakahaere i te āhua haumaru, ā, e rite ana ki ngā pūrongo o mua, e whakarato ana i te tūāpapa pono mō te maimoatanga mō te wā roa.
He aha i whiriwhiri ai koe i te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing?
Hei pokapū hauora o te ao e arotahi ana ki te tiaki mate pukupuku tika, ka tukuna e mātou ki ngā tūroro o te ao:
- Rōpū hauora reo maha: He ratonga kei roto i te reo Hainamana, Ingarihi, Rūhia, Ārapi, me ētahi atu, kia pai ai te whakawhitiwhiti kōrero puta noa.
- Ngā ratonga tūroro o te ao kotahi-ā-motu: Te whakaritenga motuhake mai i ngā kōrero mamao me te āwhina visa hauora ki ngā whakawhiti taunga rererangi, ngā whakaritenga hōhipera, me te whai muri i te maimoatanga.
- Ngā mahere maimoatanga whaiaro: He maimoatanga arotahi kua whakaritea me ngā mahere whakahaere whānui i runga i te āhua ira o te tūroro me tōna āhua whānui.
Whakapā mai ki a mātou i tēnei rā hei tīmata i tō haerenga o te tumanako
Te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing
Waea Tūroro Ao Whānui: 400-880-3716
WeChat: 17801183037
Īmēra:
- 100085_010@163.com
- myimmnet@163.com
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Me whiwhi tō oranga i te maimoatanga pai rawa atu
Ahakoa kei te rapu koe i te huarahi tuatahi mō te tumanako, kua ahu whakamua rānei koe i muri i ngā maimoatanga maha o mua, tera pea ka tukuna e te sevabertinib tētahi huringa hou onge. Kua rite te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing ki te whakatuwhera i tētahi ara matomato māu—waea mai ki 400-880-3716 inaianei, whakapā mai rānei mā WeChat, īmēra rānei. Tukua mātou kia āwhina i a koe ki te hono atu ki ngā tohunga matua, ki te aromatawai i te tika, me te whakamahere i tō haerenga maimoatanga ki Haina.
Kaua e tatari. He tīmatanga hou pea ia waeatanga.
Te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing — Te Hononga i ngā Tūroro o te Ao ki te Rongoā Tika o Haina.
Wā tuku: Paenga-whāwhā-16-2026