Kua Whakaaetia ngā Papa Glecirasib Citrate mō te Whakarewatanga Mākete, he Upoko Hou i roto i te Maimoatanga NSCLC Matatau kua Mutatedhia e KRASG12C

I te 22 o Mei, 2025, i panuitia e Allist Pharmaceuticals kua whakaaetia mana te whakarewatanga mākete o tā rātou rongoā auaha Airuikai (Glecirasib Citrate Tablets), he aukati KRAS-G12C. Mā te whakaaetanga ka taea te whakamahi i a Airuikai hei rongoā i ngā tūroro pakeke me te mate pukupuku pūkahukahu kore-pūtau iti kua whakarerekētia e KRAS®®G12C (NSCLC) kua whiwhi i te iti rawa i te kotahi raina rongoā pūnaha. He tohu tēnei i tētahi atu rongoā mate pukupuku pūkahukahu auaha kua whakaaetia mō Allist Pharmaceuticals, e tuku ana i tētahi kōwhiringa maimoatanga hou mō ngā tūroro me te mate pukupuku pūkahukahu kore-pūtau iti kua whakarerekētia e KRASG12C (NSCLC) me te āwhina ki te hanga anō i te whenua maimoatanga mō tēnei momo mate pukupuku uaua ki te rongoā.

Ko te whakaaetanga i ahu mai i ngā hua o tētahi rangahau matua Wāhanga II mō te ringa kotahi e aromatawai ana i te haumaru, te manawanui, me te whai huatanga o te rongoā kotahi a Glecirasib i roto i ngā tūroro he mate pukupuku pūkahukahu kore-pūtau iti kei roto ngā whakarerekētanga KRASG12C kua rahua, kāore rānei i manawanui ki ngā maimoatanga paerewa.

I whakaatuhia e ngā hua he whai hua a Goleresai, ā, he pai hoki te manawanui ki te rongoā. I te 28 o Hepetema, 2024, e 119 ngā tūroro NSCLC katoa i whakaurua ki te tātari. Ko te reiti urupare whai take kua whakaūtia (cORR), i aromatawaitia e te Komiti Arotake Motuhake (IRC), he 49.6% (40.2%-59.0%), me te reiti whakahaere mate (DCR) he 86.3% (78.7%-92.0%). Ko te roanga waenga o te urupare (DOR) he 14.5 marama (9.6 marama ki te kore e taea te whakatau tata), ko te oranga kore-haere whakamua (PFS) he 8.2 marama (5.2–11.1), ā, ko te oranga whānui (OS) he 17.5 marama (13.6 marama ki te kore e taea te whakatau tata).

I tēnei wā, he maha tonu ngā whakamātautau haumanu o ngā hangarau hou hei ārai i te matepukupuku i Haina e rapu ana i ngā tūroro. Mēnā kei te hiahia koe ki te kōrero mō ngā rongoā me ngā hangarau hou, ka taea e koe te whakapā atu ki te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing.

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