Nō nā tata nei, i muri i te whiwhinga o te rongoā pūtau KD-496 CAR-T, ka mau tonu te whakahekenga o te puku i roto i tētahi tūroro mate pukupuku repe taikaha kua pāngia e te mate pukupuku repe taikaha kua whanake haere, ā, kāore i angitu i roto i ngā momo maimoatanga maha o mua.
I tēnei wā, he maha tonu ngā whakamātautau haumanu o ngā hangarau hou hei ārai i te matepukupuku i Haina e rapu ana i ngā tūroro. Mēnā kei te hiahia koe ki te kōrero mō ngā rongoā me ngā hangarau hou, ka taea e koe te whakapā atu ki te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing.
Tau Waea：4008803716
WeChat ID: 17801183037
Īmēra：myimmnet@163.com
I te marama o Hūrae 2021, i kitea he puranga o te pane o te pancreas, he mea ārai hoki i te awaawa o raro o te pancreas, ā, i muri mai ka kitea he puku puku, tata ki te 3 cm te rahi, i te tukanga uncinate o te pane o te pancreas. Nā te whakamātautau mate i whakaū te mate pukupuku adenocarcinoma kua rerekē te āhua. I muri i te pokanga, i whiwhi ia i te paclitaxel (nab-paclitaxel) i herea ki te albumin me te chemotherapy S-1, ā, i muri mai ko te M108 + nab-paclitaxel + gemcitabine me te LM108 i honoa ki te toripalimab. He hītori tōna mō te schizophrenia me te mate huka, ā, i pai te whakahaere i ngā rongoā e rua.
I te marama o Pēpuere 2025, i whiwhi te tūroro i te werohanga o ngā pūtau KD-496 CAR-T. I te aromatawai tuatahi o te pukupuku i muri i ngā wiki e whā, ahakoa tōna koroheketanga me te taumaha o te pukupuku (te whara whāinga turanga o te 58 mm), kua whakaitihia te whara whāinga mā te 34.5% mai i te turanga. I te rā 60, kua heke haere te whara whāinga mā te 37.9%, ā, i ngā rā 90 me te 180, ka haere tonu te whakaiti i te pukupuku mā te 44.8%, me te pupuri i te urupare wāhanga (PR) me te kore he paitini nui ki te puku, ki te roro rānei.
I te Hui-tanguru 2023, i pokaina tētahi tūroro mate pukupuku puku, e 70 tau te pakeke, ā, i muri i te pokanga, i kitea he adenocarcinoma ulcerative āhua rerekē, kāore i te tino rerekē, kua horapa kē ki ngā kōpuku lymph, te peritoneum, me ngā pukahukahu e rua, me te ascites me te pleural effusion (he mate kua horapa whānuitia, kua horapa whānuitia). E waru wiki i muri i te pokanga, i whiwhi ia i te SOX chemotherapy (oxaliplatin + S-1), engari i haere tonu tōna āhua. Ko ngā nganatanga i muri mai ki te PX (paclitaxel) + PD-1 (immunotherapy) mō ngā huringa e whā, ā, i muri mai ko te capecitabine + nivolumab, kāore i taea te aukati i te haere whakamua. Hei whakamutunga, i tukuna te nivolumab + fruquintinib (he rongoā anti-angiogenic), engari he iti noa te whai huatanga.
I te rā 28 o te rongoā CAR-T, kua iti haere te puku mā te 47.3% i whakaritea ki te wā i mua i te maimoatanga, ā, kua eke ki te tauhohenga wāhanga hōhonu (PR). I te rā 60, ka haere tonu te iti haere o te puku mā te 41.9%, me te pupuri i te PR kua whakaūtia, e tohu ana i te maimoatanga pumau me te whai hua.
I te marama o Noema 2023, i tangohia he pokanga puku i te puku, ā, i muri i te pokanga, i kitea he adenocarcinoma kāore i te tino rerekē te āhua, me te carcinoma pūtau signet-ring wāhanga (tino kino). I whakamātau ia i ngā tikanga chemotherapy me te immunotherapy maha, tae atu ki te oxaliplatin + capecitabine + sintilimab, oxaliplatin + leucovorin + sintilimab, nab-paclitaxel + sintilimab + fruquintinib, me te irinotecan monotherapy. Heoi, i te marama o Pēpuere 2025, i tere haere te whanaketanga o tōna āhua, ā, kāore i whai hua ngā maimoatanga tuku iho.
I muri mai ka whiwhi ia i te rongoā pūtau CAR-T, ā, i te rā 28, kua mimiti te pukupuku mā te 31.8% i whakaritea ki tō mua i te maimoatanga, ā, kua tutuki he urupare hapa (PR), ā, i angitu te whakahaere i te mate.
I tēnei wā, he maha tonu ngā whakamātautau haumanu o ngā hangarau hou hei ārai i te matepukupuku i Haina e rapu ana i ngā tūroro. Mēnā kei te hiahia koe ki te kōrero mō ngā rongoā me ngā hangarau hou, ka taea e koe te whakapā atu ki te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing.
Tau Waea：4008803716
WeChat ID: 17801183037
Īmēra：myimmnet@163.com
Te wā tuku: Hurae-31-2025