Nō nā tata nei, i whakaaetia mana e te Whakahaere Hua Hauora ā-Motu o Haina te whakakotahitanga o te rongoā Anlotinib Hydrochloride me te Penpulimab e Chia Tai Tianqing mō te maimoatanga tuatahi o te mate pukupuku ate kua matatau. Koinei te tekau o ngā tohu kua whakaaetia mō te Anlotinib Hydrochloride, he tohu i tētahi kōwhiringa auaha nui i roto i te mara o te rongoā mate pukupuku ate matatau. Ko tēnei rongoā e ahu mai ana i tētahi rangahau haumanu Wāhanga III i whakaputaina i roto i te hautaka oncology rongonui o te ao *The Lancet Oncology*, me ōna raraunga whai hua whakamiharo e kawe mai ana i te tumanako hou ki ngā tūroro puta noa i te ao.
**Te Aranga Rangahau: Ka Whakaroa i te Ora, ka Whakaiti i te Mōrearea o te Mate**
Ko te rangahau, ko ALTN-AK105-III-02 te ingoa, he whakamātautau haumanu Wāhanga III maha-pokapū, matapōkeretia, tuwhera-tapanga, whakahaere-whakarara i hangaia hei aromatawai i te mahi a te Anlotinib Hydrochloride i honoa ki te Penpulimab ki te whakataurite ki te rongoā paerewa tuku iho a Sorafenib i roto i te maimoatanga raina tuatahi o te mate pukupuku ate pūtau matatau. I whakaurua e te rangahau te katoa o te 649 ngā tūroro mate pukupuku ate matatau, tata ki te 41% o rātou i pangia e te whakaekenga macrovascular, ā, tata ki te 49.2% he taumata alpha-fetoprotein teitei (≥400 ng/mL). Ko ēnei āhuatanga e tohu ana i ngā wero maimoatanga nui ake.
He mea whakatenatena ngā hua o te rangahau:
- **Te Roa Nui o te Oranga Kore-Whakahaere:** Ko te wā oranga toharite mō te kore-whakahaere i roto i te rōpū whakaora whakakotahi i eke ki te 6.9 marama, he nui ake i te 2.8 marama i roto i te rōpū whakahaere, me te 47% te hekenga o te mōrearea o te whanaketanga o te mate, o te mate rānei.
- **He Whakapainga Kitea mō te Oranga Whānui:** Ko te oranga whānui toharite i roto i te rōpū whakaora whakakotahi he 16.5 marama, ki te whakaritea ki te 13.2 marama i roto i te rōpū whakahaere, e tohu ana i te 31% te whakahekenga o te mōrearea o te mate.
Ehara i te mea ko ngā painga o tēnei rongoā te whakaroa i te haere whakamua o te mate anake e whakaatuhia ana e ēnei raraunga "pūtake pai takirua", engari e whakaatu ana hoki i ngā putanga nui o ngā painga oranga whānui, e tuku ana i ngā kōwhiringa maimoatanga whai hua ake mō ngā tūroro e pangia ana e te mate pukupuku ate kua whanake haere.
**Te Tari Ao o te Hōhipera Oncology o te Rohe Tonga o Beijing: Tō Hoa Ārai Matepukupuku o te Ao**
I te aroaro o te mate pukupuku, he mea nui te urunga wawe ki ngā mōhiohio hauora whai mana me te tautoko maimoatanga ngaio. E whakapau kaha ana te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing ki te whakarato ratonga tātaritanga me te maimoatanga oncology whānui mō ngā tūroro o te ao, tae atu ki ngā kōrerorero mō ngā maimoatanga hou, te whakamahere maimoatanga whaiaro, me te āwhina whakawhitiwhiti kōrero reo-maha. Ka mahi tahi mātou me ngā umanga rangahau o te motu me te ao kia whai hua ai ngā tūroro mai i ngā whanaketanga hou pēnei i te rongoā whakakotahi Anlotinib Hydrochloride.
**Ngā Mōhiohio Whakapā: Kei konei mātou hei mahi māu**
Mena kei te rapu koe, tō whānau rānei i ngā huarahi maimoatanga mō te mate pukupuku ate kua horapa, me ētahi atu pukupuku rānei, tēnā whakapā mai ki a mātou mā roto i ēnei tikanga. Ka whakaratohia e tā mātou tīma ngaio ngā tohutohu taipitopito mō te rongoā, ngā aratohu tukanga hauora, me te tautoko mō ngā tūroro o tāwāhi:
- **Waea:** 400-880-3716
Waea mai ki tēnei nama waea hei kōrero tika ki ā mātou kaiwhakahaere tūroro o te ao mō ngā kōrero tere me te āwhina i te whakarite wā.
- **WeChat:** 17801183037
Tāpirihia tā mātou pūkete WeChat mana hei whiwhi i ngā mōhiohio maimoatanga wā-tūturu, ngā pātai ipurangi, ngā kōrerorero ataata rānei.
- **Īmēra:**
① 100085_010@163.com
② myimmnet@163.com
Tukuna mai ō tuhinga hauora, ō pātai rānei ki tā mātou īmēra, ā, mā tā mātou tīma tohunga e tuku mai ngā tūtohutanga maimoatanga whaiaro.
**He aha mātou i whiriwhiri ai?**
- **Te Uru Atu ki ngā Maimoatanga Hou:** Ka whai tonu mātou i ngā au o te maimoatanga mate pukupuku o te ao kia whai wāhi ai ngā tūroro ki te whiwhi i ngā otinga auaha pēnei i te maimoatanga whakakotahitanga Anlotinib Hydrochloride.
- **Ratonga Reo Maha:** Ka tautoko mātou i ngā reo maha, tae atu ki te reo Pākehā, hei whakakore i ngā arai whakawhitiwhiti kōrero, hei whakarite hoki i tētahi wheako maeneene mō ngā tūroro o tāwāhi.
- **Āwhina Whānui:** Mai i ngā tono visa me ngā whakaritenga wāhi noho ki ngā mahi whai muri i te maimoatanga, ka whakaratohia e mātou he ratonga aro nui kotahi-mutunga.
He whakataetae ki te wā te maimoatanga mate pukupuku. Nā te whakaaetanga o te rongoā whakakotahitanga Anlotinib Hydrochloride kua kawea mai he tumanako hou ki ngā tūroro e pangia ana e te mate pukupuku ate kua whanake haere. Ahakoa kei hea koe, kua rite te Tari Ao o te Hōhipera Oncology Rohe Tonga o Beijing hei hoa pumau māu i roto i tō haerenga ārai-mate pukupuku. Whakapā mai ki a mātou i tēnei rā hei tīmata i tō haerenga maimoatanga whaiaro!
**Kia maumahara ki ā mātou mōhiohio whakapā:**
Waea: 400-880-3716
WeChat: 17801183037
Email: 100085_010@163.com or myimmnet@163.com
Kei te tumanako mātou ki te whakarato ki a koe i te tautoko hauora ngaio, aroha hoki!
Wā tuku: Hanuere-27-2026