Ko te putanga hou o te World Health Organization's World Health Organization's Classification of Soft Tissues and Bone Tumors, i whakaputaina i te Paenga-whāwhā 2020, e whakarōpū ana ingā sarcomaski ngā kāwai e toru: sngā pukupuku kiko maha, ngā pukupuku wheua, me ngā pukupuku o te wheua me te kiko ngohengohe me ngā pūtau porowhita iti kāore i te wehewehea(pērā i te EWSR1-kore-ETS fusion round cell sarcoma).
"Te Mate Pukupuku Kua Warewaretia"
He momo onge te sarcomamate pukupuku i roto i ngā pakeke, e whakaaro ana mō te tata ki1%o ngā mate pukupuku pakeke katoa, e kiia ana ko "Te Mate Pukupuku Kua Warewaretia." Heoi, he āhua noa ihohe mea noa i roto i ngā tamariki, te whakaaro mō te taha15% ki te 20%o ngā mate pukupuku katoa o ngā tamariki. Ka taea te puta i ngā wāhanga katoa o te tinana, ko te nuinga i roto i tengā ringaringa, ngā waewae rānei(60%), ā, whai muri ko tetinana, puku rānei(30%), ā, hei whakamutunga ko teupoko, kaki rānei(10%).
I ngā tau tata nei, kua piki haere te maha o ngā pukupuku wheua me ngā kiko ngohengohe. Ko ngā pukupuku wheua kino tuatahi he mea noa ake i roto i ngā taiohi me ngā tāngata pakeke, tae atu ki te osteosarcoma, te Ewing sarcoma, te chondrosarcoma, te malignant fibrous histiocytoma, me te chordoma, me ētahi atu. Ko ngā pukupuku kiko ngohengohe noa ko te synovial sarcoma, te fibrosarcoma, te liposarcoma, me te rhabdomyosarcoma. Ko ngā metastases wheua he mea noa ake i roto i ngā tāngata pakeke me ngā kaumātua, ko ngā pukupuku tuatahi noa ko te mate pukupuku pūkahukahu, te mate pukupuku ū, te mate pukupuku tākihi, te mate pukupuku prostate, me te mate pukupuku tairoi, me ētahi atu.
Te Kitenga Moata, Te Maimoatanga Moata – Te Whakamārama i ngā "Puku" Huna
Nā te nui o te hokinga mai o ngā sarcomas, he maha ngā pukupuku kāore i te mārama ngā tātaritanga i mua i te pokanga, ā, kāore hoki he whakamātautau whakaahua taipitopito. He maha ngā wā ka kitea i te wā pokanga kāore te pukupuku i te ngāwari pērā i te whakaaro i mua i te pokanga, ka hua ake he tangohanga kāore i oti. Tērā pea ka puta te hokinga mai, te metastasis rānei i muri i te pokanga, ka ngaro i ngā tūroro te whai wāhitanga maimoatanga pai rawa atu. Nō reira,He pānga nui te kitenga wawe, te tautuhi tika, me te maimoatanga wā-poto ki te oranga o ngā tūroro. I tēnei rā, e hiahia ana mātou ki te whakamōhio atu ki tētahi tohunga rongonui, he tata ki te 20 tau te roa o tana wheako ki tēnei mahi.i roto i te tātaritanga paerewa me te maimoatanga whaiaro o te sarcoma kiko ngohengohe, ā, e tino whakanuia ana e te umanga me ngā tūroro –TākutaLiu Jiayongmai i te Tari Wheua me te Kiko Ngāwari i te Hōhipera Matepukupuku o Te Whare Wānanga o Peking.
Te Whakakite i te Tohunga me te Mātauranga Hōhonu mō te Mamae o te Wheua me te Kikokiko – Tākuta.Liu Jiayong
Tākuta Rongoā, Tākuta Matua, Ahorangi Tuarua. I ako i te Anderson Cancer Center i te Hononga o Amerika.
Tohungatanga:Te rongoā whānui mō ngā sarcomas kiko ngohengohe (te tango me te hanga anō i te pokanga; te chemotherapy, te rongoā arotahi, me te immunotherapy); te rongoā pokanga mō ngā melanomas.
E tata ana ki te 20 tau o te wheako hauora, kua kohia e Tākuta Liu Jiayong te nui o ngā pūkenga haumanu me ngā pūkenga pokanga i roto i te maimoatanga.tātaritanga paerewa me ngā mahere maimoatanga whaiaromō ngā sarcoma kiko ngohengohe noa pērā i te undifferentiated pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, adenocystic carcinoma-like sarcoma, epithelioid sarcoma, fibrosarcoma, angiosarcoma, me te infiltrative fibromatosis. He tino tohunga iaHe tohunga ki te whakahaere i ngā oko toto me ngā io i te wā e tangohia ana te sarcoma o te peka, tae atu ki te whakatika me te hanga anō i ngā hapa o ngā kiko ngohengohe o te kiri.Ka whakarongo puku a Tākuta Liu ki ia tūroro, ka pātai mārire mō ō rātou hītori hauora, ā, ka tangohia hoki ngā pūkete hauora tino tika. Ka aro nui ia ki ngā huringa o te āhua o te tūroro i ngā wā rerekē, pērā i mua me muri i te pokanga, i te wā e rongoatia ana, i te aroturukitanga, me te haere whakamua o te mate, me te whakatau tika me te whakarerekē i ngā mahere maimoatanga i te wā tika.
I tēnei wā, kei te mahi a Tākuta Liu Jiayong hei mema mō te Soft Tissue Sarcoma and Melanoma Group o te Chinese Anti-Cancer Association, me te mema anō hoki mō te Bone Tumor Group o te Beijing Society of Orthopedics of the Chinese Medical Association.I te tau 2010, ko ia te tuatahi i Haina ki te whakamāori me te whakaputa i ngā "NCCN Clinical Practice Guidelines in Soft Tissue Sarcoma," e whakatairanga ana i te maimoatanga whānui paerewa o ngā sarcoma kiko ngohengohe.Ahakoa te nui o ngā tūroro e whai ana ia kia ahu whakamua, e whakapau kaha ana hoki ia ki te rangahau haumanu me te pūtaiao. He tangata pono, he tangata kawenga hoki ia mō ia tūroro e rongoatia ana e ia, ā, i te wā o te mate urutā, i aro atu ia ki ngā uauatanga i pā ki ngā tūroro e rapu ana i te tiaki hauora mā te whakautu wawe ki ngā kōrero a te tūroro, te arotake i ngā hua o te whai muri mai, me te whakarato i ngā taunakitanga maimoatanga tika mā roto i ngā papaaho kōrero ipurangi pērā i te Good Doctor's Patient Group.
Kēhi Tata Nei
I te tīmatanga o te tau 2019, i pāngia a Mr. Zhang, he tūroro 35-tau te pakeke, e te ngaronga o te tirohanga. I muri mai, i pokangahia ia ki te tango i te pūmua o te kanohi maui nā te pikinga tonu o te pēhanga o roto o te kanohi. I whakaatuhia e te mate i muri i te pokanga he pukupuku mumura. I te raumati o taua tau anō, i kitea he maha ngā pona pūkahukahu i te wā o te tirotiro whai muri, engari kāore i kitea he pūtau pukupuku mā roto i ngā biopsies ngira. I whakaatuhia e ngā tirotiro whai muri he maha ngā metastases wheua me te pūkahukahu. I kitea ia e ngā whakawhitiwhiti kōrero i ngā hōhipera ā-rohe me ngā hōhipera taumata teitei he pukupuku mumura myofibroblastic. I te marama o Ākuhata 2022, i tukuna ia ki te chemotherapy horopeta nui, i tino whakaora i tōna mamae engari kāore i kitea he whakapainga i roto i ngā whara i te arotakenga anō. I ngoikore hoki tōna āhua tinana. Ahakoa tēnei, kāore tōna whānau i mutu te tumanako. Whai muri i te rapu whakaaro maha, ka tae atu rātou ki te Tākuta Liu Jiayong i te Whiringa-ā-rangi 2022. Whai muri i te arotake i te hītori hauora o te tūroro, ngā tuhinga hauora katoa, ngā whakamātautau pathological, me ngā raraunga whakaahua,TākutaI whakaarohia e Liu tētahi tikanga rongoā chemotherapy e whai kiko ana i te methotrexate iti-hohenga me Changchun Ruibin.He iti te utu o tēnei tikanga rongoā matū, ā, he iti noa ngā pānga taha. I muri i ngā rā 35 o te rongoā, i whakaatuhia e te karapa CT whai muri kua ngaro te puranga i roto i te pukahukahu matau, e tohu ana i te whakahaere pai o te pukupuku.I kitea i roto i tētahi whakamātautau whai muri tata nei i te Hōhipera Oncology Rohe Tonga o Beijing te āhua pumau o te pukahukahu, ā, i tūtohu a Tākuta Liu kia haere tonu ngā tirotiro whai muri. Inaianei kua nui ake te whakapono o te tūroro me tōna whānau ki te maimoatanga e whai ake nei, me te tumanako nui. E whakaaro ana rātou kua kite rātou i tētahi hihi o te māramatanga i roto i te haerenga o te maimoatanga, ā, e whakaatu ana i tō rātou whakawhetai nui mā te whakaatu i tētahi haki mihi.
Wā tuku: 25 o Ākuhata-2023